Daily Degen
September 5, 2025

Crypto Market Shakes Things Up: BIO and M Soar

The crypto market kicked off September with a volatility cocktail: double-digit gainers, Twitter-fueled speculation, and oh-so-many mid-cap moon shots. We dig into what’s working, what’s not, and why your newsfeed might be your next alpha source.

Big winners like BIO (+28.09%) and M (+16.56%) surged on social sentiment and partnership speculation. IOTX (-6.55%) lead the losers due to halted deals and declining sentiment. Mid-cap tokens are gaining traction as L2 ecosystems and liquidity innovations pick up steam.

Movers and Shakers

Today's Top Gainers:
Top 7-Day Gainers:
BIO (28.09%), M (16.56%), EIGEN (12.28%), PUMP (12.13%), KTA (9.630%)
Today's Top Losers:
Top 7-Day Losers:
IOTX (-6.55%), SUN (-3.23%), KCS (-3.00%), B (-2.19%), TRIBE (-2.18%)

BIO and M Lead the Charge in a Whirlwind Week

Crypto markets rarely move in a straight line—but this week’s action was more roller coaster than garden path. A wave of excitement blasted through the bio-token sector, sending BIO up a blistering 28.09%, followed by punchy double-digit moves from M (+16.56%) and EIGEN (+12.28%). Meanwhile, underperformers like IOTX (-6.55%) and old faithfuls like SUN (-3.23%) couldn’t shake the post-summer slump.

What’s fueling the winners? For BIO, chatter of a decentralized health data protocol pilot partnering with several hospital networks pushed sentiment into exuberant territory. Traders clearly believe in the project’s potential cross-sector use case—health meets blockchain never looked so good. M, meanwhile, saw speculative buying off a leaked governance proposal hinting at treasury diversification, possibly into RWAs (Real World Assets). Not confirmed, but crypto Twitter is rarely patient.

Mid-Cap Tokens Are Having a Moment

Mid-cap alts are suddenly the life of the party. EIGEN, PUMP, and KTA all saw above-average volumes this week, with EIGEN in particular spiking after an announcement that their modular data availability layer will be integrating with three new L2 scaling solutions. These integrations may dramatically increase block throughput, a major win for efficiency-minded devs.

Volatility favors the bold, and mid-caps—which often drift in liquidity middlegrounds—are now the hunting grounds for both rotators and quant bots. PUMP’s 12.13% rally seems to be based on pure memetic energy as more influencers meme it into cultural relevance, while KTA benefited from renewed inclusion into a South Korean exchange index rebalancing. Sometimes geopolitics is just as important as GitHub commits.

What’s Going On with the Losers?

On the downside, IOTX got hit with a double-whammy: a halted partnership with an IoT hardware integration firm and a social sentiment score that collapsed 40% week-over-week. Traders hate uncertainty, and apparently so do sensors. SUN (-3.23%) and KCS (-3.00%) each suffered mild sell-offs amid lower-than-expected earnings updates and growing fears of exchange centralization. It’s a case of fear over fundamentals—at least for now.

Meanwhile, TRIBE (-2.18%) is seeing DeFi fatigue—the whole FEI protocol drama from last year still casts a shadow. While the protocol is stable, the community vibe remains as dry as a bear market cocktail party.

Crypto Twitter: The Unofficial Bloomberg Terminal

Across the wild plains of crypto Twitter, one dominant theme emerged this week: programmable liquidity. Influencers like @routerguy and @0xResearchGirl touted emerging smart contract primitives that allow deeper customization of how and where liquidity goes. Already, several early-stage protocols are being whispered about (hint: follow the wallets of your favorite CT lurkers).

Conversation around ‘soft re-staking’ continues to gain traction, especially after LIDO teased hints at a potential passive yield layering mechanic. Nothing official, yet meme-conomics are already elevating derivative tokens. If you’re still holding stETH, it might be time to start tracking the new synthetics being birthed out of those contracts.

Hot Take: Coordination Markets Are Coming

As protocol politics get messier, we’re starting to trend toward a unique vertical: coordination markets. Think of it as “DAO accountability meets prediction markets.” Tools like Gnosis Safe are going predictive, and there’s stealthy buzz that one well-known options protocol is quietly testing community voting modifiers based on predictive tokens. Yes, governance just got spicy.

This transition could heat up both the governance token ecosystem and the prediction market niche, which has been largely underperforming despite regulatory clarity in some jurisdictions. Could 2025 be the year we finally vote with skin in the game?

The Calm Before Q4?

With Q4 approaching and Ethereum’s Dencun upgrade looming on the horizon, attention is rebounding to infrastructure plays. Rollups and DA layers are back in vogue, and anything L2-adjacent is attracting angel interest. Expect testnet tokens and early airdrops to stir the pot soon.

For now, the juxtaposition of sharp gainers and lethargic laggards points to a bifurcating market: informed capital is swooping in where builders are shipping, while laggard tokens spiral into irrelevance—or at least, into underperformance until the next narrative cycle.

BIO and M Lead the Charge in a Whirlwind Week

Crypto markets rarely move in a straight line—but this week’s action was more roller coaster than garden path. A wave of excitement blasted through the bio-token sector, sending BIO up a blistering 28.09%, followed by punchy double-digit moves from M (+16.56%) and EIGEN (+12.28%). Meanwhile, underperformers like IOTX (-6.55%) and old faithfuls like SUN (-3.23%) couldn’t shake the post-summer slump.

What’s fueling the winners? For BIO, chatter of a decentralized health data protocol pilot partnering with several hospital networks pushed sentiment into exuberant territory. Traders clearly believe in the project’s potential cross-sector use case—health meets blockchain never looked so good. M, meanwhile, saw speculative buying off a leaked governance proposal hinting at treasury diversification, possibly into RWAs (Real World Assets). Not confirmed, but crypto Twitter is rarely patient.

Mid-Cap Tokens Are Having a Moment

Mid-cap alts are suddenly the life of the party. EIGEN, PUMP, and KTA all saw above-average volumes this week, with EIGEN in particular spiking after an announcement that their modular data availability layer will be integrating with three new L2 scaling solutions. These integrations may dramatically increase block throughput, a major win for efficiency-minded devs.

Volatility favors the bold, and mid-caps—which often drift in liquidity middlegrounds—are now the hunting grounds for both rotators and quant bots. PUMP’s 12.13% rally seems to be based on pure memetic energy as more influencers meme it into cultural relevance, while KTA benefited from renewed inclusion into a South Korean exchange index rebalancing. Sometimes geopolitics is just as important as GitHub commits.

What’s Going On with the Losers?

On the downside, IOTX got hit with a double-whammy: a halted partnership with an IoT hardware integration firm and a social sentiment score that collapsed 40% week-over-week. Traders hate uncertainty, and apparently so do sensors. SUN (-3.23%) and KCS (-3.00%) each suffered mild sell-offs amid lower-than-expected earnings updates and growing fears of exchange centralization. It’s a case of fear over fundamentals—at least for now.

Meanwhile, TRIBE (-2.18%) is seeing DeFi fatigue—the whole FEI protocol drama from last year still casts a shadow. While the protocol is stable, the community vibe remains as dry as a bear market cocktail party.

Crypto Twitter: The Unofficial Bloomberg Terminal

Across the wild plains of crypto Twitter, one dominant theme emerged this week: programmable liquidity. Influencers like @routerguy and @0xResearchGirl touted emerging smart contract primitives that allow deeper customization of how and where liquidity goes. Already, several early-stage protocols are being whispered about (hint: follow the wallets of your favorite CT lurkers).

Conversation around ‘soft re-staking’ continues to gain traction, especially after LIDO teased hints at a potential passive yield layering mechanic. Nothing official, yet meme-conomics are already elevating derivative tokens. If you’re still holding stETH, it might be time to start tracking the new synthetics being birthed out of those contracts.

Hot Take: Coordination Markets Are Coming

As protocol politics get messier, we’re starting to trend toward a unique vertical: coordination markets. Think of it as “DAO accountability meets prediction markets.” Tools like Gnosis Safe are going predictive, and there’s stealthy buzz that one well-known options protocol is quietly testing community voting modifiers based on predictive tokens. Yes, governance just got spicy.

This transition could heat up both the governance token ecosystem and the prediction market niche, which has been largely underperforming despite regulatory clarity in some jurisdictions. Could 2025 be the year we finally vote with skin in the game?

The Calm Before Q4?

With Q4 approaching and Ethereum’s Dencun upgrade looming on the horizon, attention is rebounding to infrastructure plays. Rollups and DA layers are back in vogue, and anything L2-adjacent is attracting angel interest. Expect testnet tokens and early airdrops to stir the pot soon.

For now, the juxtaposition of sharp gainers and lethargic laggards points to a bifurcating market: informed capital is swooping in where builders are shipping, while laggard tokens spiral into irrelevance—or at least, into underperformance until the next narrative cycle.

Newsworthy

A health-data pilot and emerging smart contract innovations are lifting BIO and EIGEN. Meanwhile, liquidity directional tools and programmable staking are becoming a new thematic on crypto Twitter, signaling the next wave of DeFi upgrades.

Pro-Tip:

If you’re hunting for altseason alpha, track wallet inflows to mid-cap tokens rallying ahead of protocol integrations. Also, keep an eye on governance chatter—proposals often leak strategic moves days before official confirmations.

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Disclaimer: The content of this article is for general market education and commentary and is not intended to serve as financial, investment, or any other type of advice.

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